4
6
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T4058 |
R-IMPP
|
Others; Serine/threonin kinase | Cell Cycle/Checkpoint; Metabolism; Others |
R-IMPP 是抗 PCSK9分泌的药物 (IC50=4.8 μM),靶向作用于 80S 核糖体,抑制 PCSK9 蛋白的翻译。 | |||
T68695 |
(R)-Bambuterol
|
||
Bambuterol is a prodrug of β2-agonist commonly used for the treatment of asthma and chronic obstructive pulmonary disease (COPD) with the advantage of once daily dosing and favorable side effect profile. Administration of a single-dose of R-bambuterol resulted in dose-dependent reductions in the levels of plasma LDL-C, high-density lipoprotein cholesterol (HDL-C), total cholesterol (TC), apolipoprotein B (ApoB) and apolipoprotein A1 (ApoA1) at Tmax. R-bambuterol can lower the plasma levels of LD... | |||
T28080 |
Mocravimod
KRP 203 free base,KRP-203,KRP203 |
||
Mocravimod is an agonist of sphingosine 1-phosphate receptor type 1. Mocravimod ameliorates atherosclerosis in LDL-R-/- mice. KRP-203 attenuates rat autoimmune myocarditis. KRP-203 combined with cyclosporine prolonged graft survival and abrogated transpla | |||
T36574 |
GW841819X
GW841819X |
||
GW841819X is an analogue of (+)-JQ1 and a novel inhibitor of BET bromodomains. GW841819X was a single enantiomer but of undefined chirality at the 4-position of the benzodiazepine ring3. GW841819X and JQ1 were recently discovered that bind to the acetyl-lysine binding pocket of BET bromodomains with Kd ranges from 50 to 370 nM [1]. GW841819X bounded to both the individual BD1 and BD2 domains with affinities of 46 and 52.5 nM, respectively. GW841819X-Brd3 interaction was estimated to be around 70... |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00989 |
LDLR Protein, Human, Recombinant (His)
low density lipoprotein receptor,... |
Human | HEK293 Cells |
LDLR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86 kDa and the accession number is A0A024R7D5. | |||
TMPK-01297 |
LDLR Protein, Cynomolgus, Recombinant (His)
LDLR,LDL R,LDL ... |
Cynomolgus | HEK293 Cells |
The low density lipoprotein receptor (LDLR) is the founding member of the LDL R family of widely expressed cell surface scavenger receptors. It is a cell-surface receptor that recognizes the apoprotein B100 which is embedded in the phospholipid outer layer of LDL particles. LDLR Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 86 kDa and the accession number is XP_005588053.1. | |||
TMPK-00402 |
LDLR Protein, Human, Recombinant (His & Avi)
FH,LDLCQ2,LDL R,LDLR... |
Human | HEK293 Cells |
The low density lipoprotein receptor (LDLR) is the founding member of the LDL R family of widely expressed cell surface scavenger receptors. It is a cell-surface receptor that recognizes the apoprotein B100 which is embedded in the phospholipid outer layer of LDL particles. LDLR Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 87.6 kDa and the accession number is P01130-1. | |||
TMPY-05809 |
LDLR Protein, Human, Recombinant (193D/A, His)
low density lipoprotein receptor,... |
Human | HEK293 Cells |
LDLR Protein, Human, Recombinant (193D/A, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86.19 kDa and the accession number is A0A024R7D5. | |||
TMPY-05499 |
LDLR Protein, Human, Recombinant (His), Biotinylated
LDL Receptor,LDL R |
Human | HEK293 Cells |
LDLR Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86 kDa and the accession number is A0A024R7D5. | |||
TMPY-05323 |
LDLR Protein, Human, Recombinant (mFc)
LDL R,FH,LDLCQ2,LDL ... |
Human | HEK293 Cells |
LDLR Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 111.2 kDa and the accession number is A0A024R7D5. |